Comparison of Reproductive Outcomes in ICSI Cycles Using Sperm Chip Technique and Density Gradient Technique in Men with Normal Semen Analysis

Background: Microfluidic sperm sorting procedure or chip technique is a chemical-free method of selecting using disposable chip. It new gentle alternative for processing which has been produced to obtain with higher rates motility and better morphology, as well reduce DNA fragmentation in high nearly undetectable levels. We aimed evaluate techniques on clinical pregnancy patients who underwent intracytoplasmic injection (ICSI). Methods: The whom fresh embryo transfer (ET) Day-3 5 after ICSI had performed were analyzed this prospective randomized cohort study. Results: Of those, 102 isolated (study group) while 111 swim-up (control group). No significant difference was observed between the groups terms fertilization rate ET 3rd 5th day. In having Day-3, Grade 1 embryos obtained similarly group control group. transferred Day-5 significantly more frequently study (p = 0.050). However, did not show differences both days. Conclusions: Although selection by provides advantage blastocyst quality, use does enhance success pregnancy. Clinical Trial Registration: Approval from ClinicalTrials.gov NCT03355937 approval number.